Mathivanan Lab
Exosomes
Role of extracellular matrix in cancer
Full list of Prof Mathivanan's publications in Full list of Mathivanan Lab publications in
1. Samuel, M., Fonseka, P., Sanwlani, R., Gangoda, L., Chee, S.H., Keerthikumar, S., Spurling, A., Chitti, S.V., Zanker, D., Ang, C.S., Atukorala, I., Kang, T., Shahi, S., Marzan, A.L., Nedeva, C., Vennin, C., Lucas, M.C., Cheng, L.,
Herrmann, D., Pathan, M., Chisanga, D., Warren, S.C., Zhao, K., Abraham, N., Anand, S., Boukouris, S., Adda, C.G., Jiang, L., Shekhar, T.M., Baschuk, N., Hawkins, C.J., Johnston, A.J., Orian, J.M., Hoogenraad, N.J., Poon, I.K.,
Hill, A.F., Jois, M., Timpson, P., Parker, B.S. and Mathivanan, S. (2021)
Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis.
Nature Communications.
3950.
2. Kalra, H., Gangoda, L., Fonseka, P., Chitti, S.V., Liem, M., Keerthikumar, S., Samuel, M., Boukouris, S., Al Saffar, H., Collins, C., Adda, C.G., Ang, C.S. and Mathivanan, S. (2019)
Extracellular vesicles containing oncogenic mutant β-catenin activate Wnt signaling pathway in the recipient cells.
Journal of Extracellular Vesicles.
8:1690217.
3. Zhao, K., Bleackley, M., Chisanga, D., Gangoda, L., Fonseka, P., Liem, M., Kalra, H., Al Saffar, H., Keerthikumar, S., Ang, C.S., Adda, C., Jiang, L., Yap, K., Poon, I., Lock, P., Bulone, P., Anderson, M*. and Mathivanan, S*. (2019)
Extracellular vesicles secreted by Saccharomyces cerevisiae are involved in cell wall remodelling.
Communications Biology.
2:305.
4. Fonseka, P., Liem, M., Ozcitti, C., Adda, C.G., Ang, C.S. and Mathivanan, S. (2019)
Exosomes from N-Myc amplified neuroblastoma cells induce migration and confer chemoresistance to non-N-Myc amplified cells: implications of intra-tumor heterogeneity.
Journal of Extracellular Vesicles. 8:1597614.
5. Pathan, M*., Fonseka, P*., Chitti, S.V., Kang, T., Sanwlani, R., Van Deun, J., Hendrix, A. and Mathivanan, S. (2019)
Vesiclepedia 2019: a compendium of RNA, proteins, lipids and metabolites in extracellular vesicles.
Nucleic Acids Research. D516-D519.
6. Chisanga, D., Keerthikumar, S., Pathan, M., Ariyaratne, D., Kalra, H., Boukouris, S., Mathew, N., Al Saffar, H., Gangoda,
L., Ang, C.S., Sieber, O., Mariadason, J., Dasgupta, R., Chilamkurti, N. and Mathivanan, S. (2016)
Colorectal Cancer Atlas: An integrative resource for genomic and proteomic annotations from colorectal cancer cell lines and tissue.
Nucleic Acids Research. 44(D1), D969-74.
7. Kalra, H., Simpson, R.J., Ji, H., Aikawa, E., Altevogt, P., Askenase, P., Bond, V.C., Borras, F.E., Breakefield, X., Budnik, V., Buzas, E.,
Camussi, G., Clayton, A., Cocucci, E., Falcon-Perez, J.M., Gabrielsson, S., Gho, Y.S., Gupta, D., Harsha, H.C., Hendrix, A., Hill, A.F., Inaal, J.M.,
Jenster, G., Kiang, L.S., Kramer-Albers, E-M., Llorente, A., Lotvall, J., Mincheva-Nilsson, L., Nazarenko, I., Nieuwland, R., Nolte-'t Hoen, E.N.M., Pandey, A.,
Patel, T., Piper, M.G., Pluchino, S., Prasad, T.S.K., Rajendran, L., Raposo, G., Record, M., Reid, G.E., Sanchez-Madrid, F., Schiffelers, R.M., Siljander, P.,
Stoorvogel, W., Taylor, D., Thery, C., Valadi, H., van Balkom, B.W.M., Vazquez, J., Vidal, M., Yanez-Mo, M., Zoeller, M. and
Mathivanan, S. (2012) Vesiclepedia: A compendium for extracellular vesicles with continuous community annotation. PLoS Biology. 12, e1001450.
8. Mathivanan, S., Ahmed, M. et al. (2008). Human Proteinpedia enables sharing of human protein data. Nature Biotechnology. 26, 164-7.
9. Amanchy, R., Periaswamy, B., Mathivanan, S., Reddy, R., Tattikota, S. G. and Pandey, A. (2007). A compendium of curated phosphorylation-based
substrate and binding motifs. Nature Biotechnology. 25, 285-286.
10. Gandhi, T. K. B., Zhong, J., Mathivanan, S., Karthick, L., Chandrika, K. N., Mohan, S. S., Sharma, S., Pinkert, S., Nagaraju, S., Periaswamy, B., Mishra, G., Nandakumar, K., Shen, B., Deshpande, N.,
Nayak, R., Sarker, M., Boeke, J. D., Parmigiani, G., Schultz, J., Bader, J. S. and Pandey, A. (2006). Analysis of the human protein interactome and comparison with yeast, worm and fly interaction
datasets. Nature Genetics. 3, 285-293.
127. Welsh JA, Goberdhan DCI, O'Driscoll L, Buzas EI, Blenkiron C, Bussolati B, Cai H, Di Vizio D, Driedonks TAP, et al. (2024).
Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches.
J Extracell Vesicles. 13(2):e12404.
126. Chitti SV, Gummadi S, Kang T, Shahi S, Marzan AL, Nedeva C, Sanwlani R, Bramich K, Stewart S, Petrovska M, Sen B, Ozkan A, Akinfenwa M, Fonseka P, Mathivanan S (2024).
Vesiclepedia 2024: an extracellular vesicles and extracellular particles repository.
Nucleic Acids Research. 52(D1):D1694-D1698.
125. Anand S, Nedeva C, Chitti SV, Fonseka P, Kang T, Gangoda L, Tabassum NI, Abdirahman S, Arumugam TV, Putoczki TL, Kumar S, Mathivanan S (2023).
The E3 ubiquitin ligase NEDD4 regulates chemoresistance to 5-fluorouracil in colorectal cancer cells by altering JNK signalling.
Cell Death and Disease. 14(12):828.
124. Marzan AL, Chitti SV, Gummadi S, Kang T, Ang CS, Mathivanan S. (2023)
Proteomics analysis of C2C12 myotubes treated with atrophy inducing cancer cell-derived factors.
Proteomics. e2300020.
123. Samuel M, Sanwlani R, Pathan M, Anand S, Johnston EL, Ang CS, Kaparakis-Liaskos M, Mathivanan S. (2023)
Isolation and characterization of cow, buffalo, sheep and goat milk-derived extracellular vesicles.
Cells. 12(20):2491.
122. Shekari, F., Alibhai, F. J., Baharvand, H., Borger, V., Bruno, S., Davies, O., Giebel, B., Salekdeh, G. H., Martin-Jaular, L., Mathivanan, S., Nelissen, I., Nolte-t Hoen, E., O'Driscoll, L.,
Perut, F., Pluchino, S., Pocsfalvi, G., Salomon, C., Soekmadji, C., Staubach, S, .... Nieuwland, R. (2023).
Cell culture-derived extracellular vesicles: Considerations for reporting cell culturing parameters.
Journal of Extracellular Biology. 2, e115.
121. Sanwlani R, Kang T, Gummadi S, Nedeva C, Ang CS, Mathivanan S. (2023)
Bovine milk-derived extracellular vesicles enhance doxorubicin sensitivity in triple negative breast cancer cells by targeting metabolism and STAT signaling.
Proteomics. 23(18):e2200482.
120. Loo L, Waller MA, Moreno CL, Cole AJ, Stella AO, Pop OT, Jochum AK, Ali OH, Denes CE, Hamoudi Z, Chung F, Aggarwal A, Low JKK, Patel K, Siddiquee R, Kang T, Mathivanan S, Mackay JP, Jochum W, Flatz L, Hesselson D, Turville S, Neely GG. (2023)
Fibroblast-expressed LRRC15 is a receptor for SARS-CoV-2 spike and controls antiviral and antifibrotic transcriptional programs.
PLoS Biol. 21(2):e3001967.
119. Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S. (2023)
Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia-inducing and non-inducing cancer cells.
Proteomics. 23(15):e2100314.
118. Fonseka P, Mathivanan S. (2023)
Extracellular Vesicles Biogenesis, Cargo Sorting and Implications in Disease Conditions.
Cells. 12(2):280.
117. Chitti SV, Nedeva C, Manickam R, Fonseka P, Mathivanan S. (2022)
Extracellular Vesicles as Drug Targets and Delivery Vehicles for Cancer Therapy.
Pharmaceutics. 14(12):2822.
116. Gummadi S, Kang T, Fonseka P, Chitti SV, Ang CS, Mathivanan S. (2022)
Pep2Graph: A standalone tool to analyse proteolytic cleavages by proteases from gel-based mass spectrometry data.
Proteomics. 22(22):e2200147.
115. Chi LH, Cross RSN, Redvers RP, Davis M, Hediyeh-Zadeh S, Mathivanan S, Samuel M, Lucas EC, Mouchemore K, Gregory PA, Johnstone CN, Anderson RL. (2022)
MicroRNA-21 is immunosuppressive and pro-metastatic via separate mechanisms.
Oncogenesis. 11(1), 38.
114. Farooq AU, Gembus K, Sandow JJ, Webb A, Mathivanan S, Manning JA, Shah SS, Foot NJ, Kumar S. (2022)
K-29 linked ubiquitination of Arrdc4 regulates its function in extracellular vesicle biogenesis.
Journal of Extracellular Vesilces. 11(2):e12188.
113. Samuel, M., Fonseka, P., Sanwlani, R., Gangoda, L., Chee, S.H., Keerthikumar, S., Spurling, A., Chitti, S.V., Zanker, D., Ang, C.S., Atukorala, I., Kang, T., Shahi, S., Marzan, A.L., Nedeva, C., Vennin, C., Lucas, M.C., Cheng, L.,
Herrmann, D., Pathan, M., Chisanga, D., Warren, S.C., Zhao, K., Abraham, N., Anand, S., Boukouris, S., Adda, C.G., Jiang, L., Shekhar, T.M., Baschuk, N., Hawkins, C.J., Johnston, A.J., Orian, J.M., Hoogenraad, N.J., Poon, I.K.,
Hill, A.F., Jois, M., Timpson, P., Parker, B.S. and Mathivanan, S. (2021)
Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis.
Nature Communications.
3950.
112. Chitti, S.V., Marzan, A.L., Shahi, S., Kang, T., Fonseka, P. and Mathivanan, S. (2021)
Repurposing of antibiotic sulfisoxazole inhibits lipolysis in pre-clinical model of cancer-associated cachexia.
Biology. 10(8), 700.
111. Foot, N., Gonzalez, M.B., Gembus, K., Fonseka, P., Sandow, J.P., Nguyen, T.T., Tran, D., Webb, A.I., Mathivanan, S., Robker, R.L. and Kumar, S. (2021)
Arrdc4-dependent extracellular vesicle biogenesis is required for sperm maturation
Journal of Extracellular Vesilces. 10(8):e12113.
110. Lima, L.G., Ham, S., Shin, H., Chai, E.P.Z., Lek, E.S.H., Lobb, R.J., Muller, A.F., Mathivanan, S., Yeo, B., Choi, Y., Parker, B.S. and Moller, A.(2021)
Tumor microenvironmental cytokines bound to cancer exosomes determine uptake by cytokine receptor-expressing cells and biodistribution
Nature Communications. 12(1):3543.
109. Fonseka, P.,# Kang, T., Chee, S., Chitti, S.V., Sanwlani, R., Ang, C.S. and Mathivanan, S.# (2021)
Temporal quantitative proteomics analysis of neuroblastoma cells treated with bovine milk-derived extracellular vesicles highlights the anti-proliferative properties of milk-derived extracellular vesicles.
Cells. 10(4), 750.
108. Phan, T.K.,#* Fonseka, P.,* Tixeira, R., Pathan, M., Ang, C.S., Ozkocak, D.C., Mathivanan, S.# and Poon, I.H.# (2021) Pannexin-1 channel regulates nuclear content packaging into apoptotic bodies and their size.
Proteomics.
e2000097
107. Fonseka, P.*, Chitti, S.V.*, Sanwlani, R.* and Mathivanan, S. (2021) Sulfisoxazole treatment does not inhibit the secretion of small extracellular
vesicles.
Nature Communications.
12(1):977
106. Fonseka, P., Pathan, M., Chitti, S.V., Kang, T. and Mathivanan, S. (2021) FunRich enables enrichment analysis of OMICs datasets.
Journal Molecular Biology.
433(11):166747
105. Sanwlani, R., Fonseka, P. and Mathivanan, S. (2021) Are dietary extracellular vesicles bioavailable and functional in consuming organisms?
Subcellular Biochemistry.
97:509-521
104. Marzan, A., Nedeva, C. and Mathivanan, S. (2021) Extracellular vesicles in metabolism and metabolic diseases.
Subcellular Biochemistry.
97:393-410
103. Nedeva, C. and Mathivanan, S. (2021) Engineering extracellular vesicles for cancer therapy.
Subcellular Biochemistry.
97:375-392
102. Shahi, S., Cianciarulo, C., Nedeva, C. and Mathivanan, S. (2021) Extracellular vesicles regulate cancer metastasis.
Subcellular Biochemistry.
97:275-296
101. Anand, S., Samuel, M. and Mathivanan, S. (2021) Exomeres: A new member of extracellular vesicles family.
Subcellular Biochemistry.
97:89-97
100. Atukorala, I. and Mathivanan, S. (2021) The role of post-translational modifications in targeting protein cargo to extracellular vesicles.
Subcellular Biochemistry.
97:45-60
99. Kang, T., Atukorala, I. and Mathivanan, S. (2021) Biogenesis of extracellular vesicles.
Subcellular Biochemistry.
97:19-43
98. Fonseka, P., Marzan, A. and Mathivanan, S. (2021) Introduction to the community of extracellular vesicles.
Subcellular Biochemistry.
97:3-18
97. Fonseka, P., Atukorala, I., Nedeva, C. and Mathivanan, S. (2021) A brief overview of New Frontiers: Extracellular Vesicles.
Subcellular Biochemistry.
97:509-521
96. Fuller, O., Whitham, M., Mathivanan, S. and Febbraio, M.A. (2020) Protective Effect of Exercise in Neurodegenerative Diseases: Potential role of Extracellular Vesicles.
Cells.
9(10):2182
95. Sanwlani, R., Fonseka, P., Chitti, S.V. and Mathivanan, S. (2020)
Milk-Derived Extracellular Vesicles in Inter-Organism, Cross-Species Communication and Drug Delivery.
Proteomes.
8(2):E11.
94. Shahi, S., Ang, C.S. and Mathivanan, S. (2020)
A High-Resolution Mass Spectrometry-Based Quantitative Metabolomic Workflow Highlights Defects in 5-Fluorouracil Metabolism in Cancer Cells with Acquired Chemoresistance.
Biology.
9(5):96.
93. Gangoda, L., Phan, T., Anand, S., Hulett, M. and Mathivanan, S. (2020)
Deubiquitinase enzyme STAMBP plays a broad role in both Toll-like and Nod-like receptor mediated inflammation.
European Journal of Inflammation.
January 2020.
92. Fonseka, P., Gangoda, L., Pathan, M., Angela, D.G. and Mathivanan, S. (2020)
Combinatorial treatment of curcumin or silibinin with doxorubicin sensitises high-risk neuroblastoma.
J Cancer Metastasis Treat.
6:7.
91. Bleackley, M.R., Samuel, M., Garcia-Ceron, D., Mckenna, J.A., Lowe, R.T.G., Pathan, M., Zhao, K., Ang, C.S., Mathivanan, S. and Anderson, M.A. (2020)
Extracellular vesicles from the cotton pathogen Fusarium oxysporum f. sp. vasinfectum induce a phytotoxic response in plants.
Frontiers in Plant Science.
10:1610.
90. Kalra, H., Gangoda, L., Fonseka, P., Chitti, S.V., Liem, M., Keerthikumar, S., Samuel, M., Boukouris, S., Al Saffar, H., Collins, C., Adda, C.G., Ang, C.S. and Mathivanan, S. (2019)
Extracellular vesicles containing oncogenic mutant β-catenin activate Wnt signaling pathway in the recipient cells.
Journal of Extracellular Vesicles.
8:1690217.
89. Atkin-Smith GK, Miles MA, Tixeira R, Lay FT, Duan M, Hawkins CJ, Phan TK, Paone S, Mathivanan S, Hulett MD, Chen W, Poon IKH. (2019)
Plexin B2 Is a Regulator of Monocyte Apoptotic Cell Disassembly.
Cell Reports.
7: 1821-1831.
88. Zhao, K., Bleackley, M., Chisanga, D., Gangoda, L., Fonseka, P., Liem, M., Kalra, H., Al Saffar, H., Keerthikumar, S., Ang, C.S., Adda, C., Jiang, L., Yap, K., Poon, I., Lock, P., Bulone, P., Anderson, M. and Mathivanan, S. (2019)
Extracellular vesicles secreted by Saccharomyces cerevisiae are involved in cell wall remodelling.
Communications Biology.
2:305.
87. Davalos-Salas M, Montgomery MK, Reehorst CM, Nightingale R, Ng I, Anderton H, Al-Obaidi S, Lesmana A, Scott CM, Ioannidis P, Kalra H, Keerthikumar S, Togel L, Rigopoulos A, Gong SJ, Williams DS, Yoganantharaja P,
Bell-Anderson K, Mathivanan S, Gibert Y, Hiebert S, Scott AM, Watt MJ, Mariadason JM. (2019)
Deletion of intestinal Hdac3 remodels the lipidome of enterocytes and protects mice from diet-induced obesity.
Nature Communications.
10:5291.
86. Vennin, C., Melenec, P., Rouet, R., Nobis, M., Cazet, A.S., Murphy, K.J., Herrmann, D., Reed, D.A., Lucas, M.C., Warren, S.C., Elgundi, Z., Pinese, M., Kalna, G., Roden, D., Samuel, M., ... Mathivanan, S.,
... Parkin, A., Phillips, P.A., Whitelock, J.M., Gill, A.J., Sansom, O.J., Croucher, D.R., Parker, B.L., Pajic, M., Morton, J.P., Cox, T.R. and Timpson, P. (2019)
CAF hierarchy driven by pancreatic cancer cell p53-status creates a pro-metastatic and chemoresistant environment via perlecan.
Nature Communications.
10:3637.
85. Srivastava, R., Cao, Z., Nedeva, C., Naim, S., Bachmann, D., Rabachini, T., Gangoda, L., Shahi, S., Glab, J., Menassa, J., Osellame, L., Nelson, T., Fernandez-Marrero, Y., Brown, F., Wei, A., Ke, F., O'Reilly, L.,
Doerflinger, M., Allison, C., Kueh, A., Ramsay, R., Smith, B.J., Mathivanan, S., Kaufmann, T. and Puthalakath, H. BCL-2 family protein BOK is a positive regulator of uridine metabolism in mammals.
PNAS.
116:15469-15474.
84. Baxter, A.A., Phan, T.K., Hanssen, E., Liem, M., Hulett, M.D., Mathivanan, S. and Poon, I.K.H. (2019)
Analysis of extracellular vesicles generated from monocytes under conditions of lytic cell death.
Scientific Reports. 9:7538.
83. Young, A.R., Duarte, J.D.G., Coulson, R., O'Brien, M., Deb, S., Lopata, A., Behren, A., Mathivanan, S., Lim, E. and Meeusen E. (2019)
Immunoprofiling of Breast Cancer Antigens Using Antibodies Derived from Local Lymph Nodes.
Cancers. 11. pii: E682.
82. Fonseka, P., Liem, M., Ozcitti, C., Adda, C.G., Ang, C.S. and Mathivanan, S. (2019)
Exosomes from N-Myc amplified neuroblastoma cells induce migration and confer chemoresistance to non-N-Myc amplified cells: implications of intra-tumor heterogeneity.
Journal of Extracellular Vesicles. 8:1597614.
81. Anand, S., Samuel, M., Kumar, S. and Mathivanan, S. (2019)
Ticket to a bubble ride: cargo sorting into exosomes and extracellular vesicles.
BBA - Proteins and Proteomics. pii: S1570-9639(19)30041-X.
80. Pathan, M*., Fonseka, P*., Chitti, S.V., Kang, T., Sanwlani, R., Van Deun, J., Hendrix, A. and Mathivanan, S. (2019)
Vesiclepedia 2019: a compendium of RNA, proteins, lipids and metabolites in extracellular vesicles.
Nucleic Acids Research. D516-D519.
79. Thery C, Witwer KW, Aikawa E, Alcaraz MJ, Anderson JD, Andriantsitohaina R, Antoniou A, Arab T, Archer F, Atkin-Smith GK, Ayre DC, Bach JM, Bachurski D, Baharvand H, Balaj L, Baldacchino S, Bauer NN, Baxter AA, Bebawy M, Beckham C, Bedina Zavec A,
Benmoussa A, Berardi AC, Bergese P, Bielska E, Blenkiron C, Bobis-Wozowicz S, Boilard E, Boireau W, Bongiovanni A, Borras FE, Bosch S, Boulanger CM, Breakefield X, Breglio AM, Brennan MA, Brigstock DR, Brisson A, Broekman ML, Bromberg JF, Bryl-Gorecka P,
Buch S, Buck AH, Burger D, Busatto S, Buschmann D, Bussolati B, Buzas EI, Byrd JB, Camussi G, Carter DR, Caruso S, Chamley LW, Chang YT, Chen C, Chen S, Cheng L, Chin AR, Clayton A, Clerici SP, Cocks A, Cocucci E, Coffey RJ, Cordeiro-da-Silva A,
Couch Y, Coumans FA, Coyle B, Crescitelli R, Criado MF, D'Souza-Schorey C, Das S, Datta Chaudhuri A, de Candia P, De Santana EF, De Wever O, Del Portillo HA, Demaret T, Deville S, Devitt A, Dhondt B, Di Vizio D, Dieterich LC, Dolo V, Dominguez Rubio AP,
Dominici M, Dourado MR, Driedonks TA, Duarte FV, Duncan HM, Eichenberger RM, Ekstrom K, El Andaloussi S, Elie-Caille C, Erdbrugger U, Falcon-Perez JM, Fatima F, Fish JE, Flores-Bellver M, Forsonits A, Frelet-Barrand A, Fricke F, Fuhrmann G,
Gabrielsson S, Gamez-Valero A, Gardiner C, Gartner K, Gaudin R, Gho YS, Giebel B, Gilbert C, Gimona M, Giusti I, Goberdhan DC, Gorgens A, Gorski SM, Greening DW, Gross JC, Gualerzi A, Gupta GN, Gustafson D, Handberg A, Haraszti RA, Harrison P,
Hegyesi H, Hendrix A, Hill AF, Hochberg FH, Hoffmann KF, Holder B, Holthofer H, Hosseinkhani B, Hu G, Huang Y, Huber V, Hunt S, Ibrahim AG, Ikezu T, Inal JM, Isin M, Ivanova A, Jackson HK, Jacobsen S, Jay SM, Jayachandran M, Jenster G, Jiang L,
Johnson SM, Jones JC, Jong A, Jovanovic-Talisman T, Jung S, Kalluri R, Kano SI, Kaur S, Kawamura Y, Keller ET, Khamari D, Khomyakova E, Khvorova A, Kierulf P, Kim KP, Kislinger T, Klingeborn M, Klinke DJ 2nd, Kornek M, Kosanović MM, Kovacs aF,
Kramer-Albers EM, Krasemann S, Krause M, Kurochkin IV, Kusuma GD, Kuypers S, Laitinen S, Langevin SM, Languino LR, Lannigan J, Lasser C, Laurent LC, Lavieu G, Lazaro-Ibanez E, Le Lay S, Lee MS, Lee YXF, Lemos DS, Lenassi M, Leszczynska A, Li IT,
Liao K, Libregts SF, Ligeti E, Lim R, Lim SK, Linē A, Linnemannstons K, Llorente A, Lombard CA, Lorenowicz MJ, Lorincz aM, Lotvall J, Lovett J, Lowry MC, Loyer X, Lu Q, Lukomska B, Lunavat TR, Maas SL, Malhi H, Marcilla A, Mariani J, Mariscal J,
Martens-Uzunova ES, Martin-Jaular L, Martinez MC, Martins VR, Mathieu M, Mathivanan S, Maugeri M, McGinnis LK, McVey MJ, Meckes DG Jr, Meehan KL, Mertens I, Minciacchi VR, Moller A, Moller Jorgensen M, Morales-Kastresana A, Morhayim J, Mullier F,
Muraca M, Musante L, Mussack V, Muth DC, Myburgh KH, Najrana T, Nawaz M, Nazarenko I, Nejsum P, Neri C, Neri T, Nieuwland R, Nimrichter L, Nolan JP, Nolte-'t Hoen EN, Noren Hooten N, O'Driscoll L, O'Grady T, O'Loghlen A, Ochiya T, Olivier M, Ortiz A,
Ortiz LA, Osteikoetxea X, ostergaard O, Ostrowski M, Park J, Pegtel DM, Peinado H, Perut F, Pfaffl MW, Phinney DG, Pieters BC, Pink RC, Pisetsky DS, Pogge von Strandmann E, Polakovicova I, Poon IK, Powell BH, Prada I, Pulliam L, Quesenberry P,
Radeghieri A, Raffai RL, Raimondo S, Rak J, Ramirez MI, Raposo G, Rayyan MS, Regev-Rudzki N, Ricklefs FL, Robbins PD, Roberts DD, Rodrigues SC, Rohde E, Rome S, Rouschop KM, Rughetti A, Russell AE, Saa P, Sahoo S, Salas-Huenuleo E, Sanchez C,
Saugstad JA, Saul MJ, Schiffelers RM, Schneider R, Schoyen TH, Scott A, Shahaj E, Sharma S, Shatnyeva O, Shekari F, Shelke GV, Shetty AK, Shiba K, Siljander PR, Silva AM, Skowronek A, Snyder OL 2nd, Soares RP, Sodar BW, Soekmadji C, Sotillo J,
Stahl PD, Stoorvogel W, Stott SL, Strasser EF, Swift S, Tahara H, Tewari M, Timms K, Tiwari S, Tixeira R, Tkach M, Toh WS, Tomasini R, Torrecilhas AC, Tosar JP, Toxavidis V, Urbanelli L, Vader P, van Balkom BW, van der Grein SG, Van Deun J,
van Herwijnen MJ, Van Keuren-Jensen K, van Niel G, van Royen ME, van Wijnen AJ, Vasconcelos MH, Vechetti IJ Jr, Veit TD, Vella LJ, Velot E, Verweij FJ, Vestad B, Vinas JL, Visnovitz T, Vukman KV, Wahlgren J, Watson DC, Wauben MH, Weaver A, Webber JP,
Weber V, Wehman AM, Weiss DJ, Welsh JA, Wendt S, Wheelock AM, Wiener Z, Witte L, Wolfram J, Xagorari A, Xander P, Xu J, Yan X, Yanez-Mo M, Yin H, Yuana Y, Zappulli V, Zarubova J, Zekas V, Zhang JY, Zhao Z, Zheng L, Zheutlin AR, Zickler AM,
Zimmermann P, Zivkovic AM, Zocco D, Zuba-Surma EK.
(2018) Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines.
Journal of Extracellular Vesicles.
1535750
78. Chitti, S.V., Fonseka, P. and Mathivanan, S. (2018)
Emerging role of extracellular vesicles in mediating cancer cachexia. Biochemical Society Transactions.
46(5):1129-1136
77. Anand, S., Foot, N., Ang, C.S., Gembus, K.M., Keerthikumar, S., Adda, C.G., Mathivanan, S#. and Kumar, S#. (2018)
Arrestin-domain containing protein 1 (Arrdc1) regulates the protein cargo and release of extracellular vesicles. Proteomics.
18(17):e1800266.
76. Chisanga, D., Keerthikumar, S., Mathivanan, S. and Chilamkurti, N. (2018)
Integration of heterogeneous omics data using semi-supervised network labelling to identify essential genes in colorectal cancer.
Computers & Electrical Engineering. 67, 267-277
75. Gangoda, L., Liem, M., Ang, C.S., Keerthikumar, S., Adda, C.G., Parker, B.S. and Mathivanan, S. (2017)
Proteomic Profiling of Exosomes Secreted by Breast Cancer Cells with Varying Metastatic Potential.
Proteomics. 17(23-24). doi: 10.1002/pmic.201600370
74. Mathivanan, S. (2017)
Extracellular Matrix and the Extracellular Environment.
Proteomics. 17(23-24). doi: 10.1002/pmic.2017700185
73. Witwer, K.W., Soekmadji, C., Hill, A.F., Wauben, M.H., Buzas, E.I.,
Di Vizio, D., Falcon-Perez, J.M., Gardiner, C., Hochberg, F., Kurochkin, I.V., Lotvall, J., Mathivanan, S., Nieuwland, R., Sahoo, S.,
Tahara, H., Torrecilhas, A.C., Weaver, A.M., Yin, H., Zheng, L., Gho, Y.S., Quesenberry, P. and Thery, C. (2017)
Updating the MISEV minimal requirements for extracellular vesicle studies: building bridges to reproducibility.
J Extracellular Vesicles. 6:1396823
72. Liem, M., Ang, C.S. and Mathivanan, S. (2017)
Insulin mediated activation of PI3K/Akt signalling pathway modifies the proteomic cargo of extracellular vesicles
Proteomics. 17(23-24). doi: 10.1002/pmic.201600371.
71. Samuel, M., Chisanga, D., Liem, M., Keerthikumar, S., Anand, S., Ang, C.S., Adda, C.G., Versteegen, E., Jois, M. and Mathivanan, S. (2017)
Bovine milk-derived exosomes from colostrum are enriched with proteins implicated in immune response and growth.
Scientific Reports. 1:5933
70. Meeusen, E., Lim, E. and Mathivanan, S. (2017)
Secreted tumor antigens - immune biomarkers for diagnosis and therapy.
Proteomics. 17(23-24). doi: 10.1002/pmic.201600442
69. Kang, Y., Stroud, D.A., Baker, M.J., De Souza, D.P., Frazier, A.E., Liem, M., Tull, D., Mathivanan, S., McConville, M.J., Thorburn, D.R., Ryan, M.T. and Stojanovski, D. (2017)
Sengers syndrome associated mitochondrial acylglycerol kinase, is a subunit of the human TIM22 protein import complex.
Molecular Cell. 3:457-470
68. Vo, J.L., Martinez Ortiz, G.C., Subedi, P., Keerthikumar, S., Mathivanan, S., Paxman, J.J. and Heras, B. (2017)
Autotransporter adhesins in Escherichia coli pathogenesis.
Proteomics. 17(23-24). doi: 10.1002/pmic.201600431
67. Pathan, M., Keerthikumar, S., Chisanga, D., Alessandro, R., Ang, C.S., Askenase, P., Batagov, A.O., Benito-Martin, A., Camussi, G., Clayton, A., Collino, F., Di Vizio, D., Falcon-Perez, J.M., Fonseca, P., Fonseka, P.,
Fontana, S., Gho, Y.S., Hendrix, A., Nolte-'t Hoen, E., Iraci, N., Kastaniegaard, K., Kislinger, T., Kowal, J., Kurochkin, I.V., Leonardi, T., Liang, Y., Llorente, A., Lunavat, T.R., Maji, S., Monteleone, F., Overbye, A.,
Panaretakis, T., Patel, T., Peinado, H., Pluchino, S., Principe, S., Ronquist, G., Royo, F., Sahoo, S., Spinelli, C., Stensballe, A., Thery, C., van Herwijnen, M., Wauben, M., Welton, J., Zhao, J. and Mathivanan, S. (2017)
A novel community driven software for functional enrichment analysis of extracellular vesicles data.
J Extracellular Vesicles. 1:1321455.
66. Jan Van Deun, Pieter Mestdagh, Patricia Agostinis, Geert Berx, Jan Gettemans, Bernd Giebel, Andrew Hill, Mathivanan, S., Esther Nolte-t-Hoen, Michael Pfaffl, Susmita Sahoo, Johan Swinnen, Clotilde Thery, Guillaume Van Niel, Marca Wauben, Kenneth Witwer, Olivier De Wever, Jo Vandesompele, An Hendrix. (2017)
EV-TRACK: transparent reporting and centralizing knowledge in extracellular vesicle research.
Nature Methods. 14(3):228-232.
65. Dona, M., Prendergast, L., Mathivanan, S., Keerthikumar, S. and Salim, A. (2017) Powerful differential expression analysis incorporating network topology for next-generation sequencing data.
Bioinformatics. 33:1505-1513.
64. Pathan. M., Samuel, M., Keerthikumar, S. and Mathivanan, S. (2017) Unassigned MS/MS Spectra: Who Am I? Methods in Molecular Biology. 1549:67-74.
63. Anand, S., Samuel, M., Ang, C.S., Keerthikumar, S. and Mathivanan, S. (2017) Label-Based and Label-Free Strategies for Protein Quantitation. Methods in Molecular Biology. 1549:31-43.
62. Chisanga, D., Keerthikumar, S., Mathivanan, S. and Chilamkurti, N. (2017) Network Tools for the Analysis of Proteomic Data. Methods in Molecular Biology. 1549:177-197.
61. Keerthikumar, S. and Mathivanan, S. (2017) Proteotypic Peptides and Their Applications. Methods in Molecular Biology. 1549:101-107.
60. Keerthikumar, S. and Mathivanan, S. (2017) Proteomic Data Storage and Sharing. Methods in Molecular Biology. 1549:5-15.
59. Keerthikumar, S., Gangoda, L., Gho, Y.S. and Mathivanan, S. (2017) Bioinformatics Tools for Extracellular Vesicles Research. Methods in Molecular Biology. 1545:189-196
58. Lasser, C., Thery, C., Buzas, E. I., Mathivanan, S., Zhao, W., Gho, Y. S., Lotvall, J. (2016) The International Society for Extracellular Vesicles launches the first massive open online course on extracellular vesicles.
Journal of Extracellular Vesicles. 16;5: 34299.
57. Kang, Y., Baker, M.J., Liem, M., Louber, J., McKenzie, M., Atukorala, I., Ang, C.S., Keerthikumar, S., Mathivanan, S. and Stojanovski, D. (2016)
Tim29 is a novel subunit of the human TIM22 translocase and is involved in complex assembly and stability.
eLife. Aug 24;5. pii: e17463.
56. Gangoda, L. and Mathivanan, S. (2016)
Cortactin enhances exosome secretion without altering cargo.
Journal of Cell Biology. 214 (2): 129.
55. Cheung, KH., Keerthikumar, S., Roncaglia, P., Subramanian, SL., Roth, ME., Gould, S., Alexander, R., Galas, D., Gerstein, MB., Hill, AF., Kitchen, RR., Lotvall, J., Patel, T., Procaccini, DC., Queensberry, P., Rozowsky, J., Raffai, RL., Shypitsyn, A., Su, AI., Thery, C., Vickers, K., Wauben, M., Mathivanan, S., Milosavljevic, A. and Laurent, L. (2016).
Extending Gene Ontology in the Context of Extracellular RNA and Vesicle Communication. Journal of Biomedical Semantics. 7:19.
54. Mackenzie, K.D., Foot, N.J., Anand, S., Dalton, H.E., Chaudhary, N., Collins, B.M., Mathivanan, S. and Kumar, S. (2016)
Regulation of the divalent metal ion transporter via membrane budding.
Cell Discovery. 2, 16011.
53. Chisanga, D., Keerthikumar, S., Pathan, M., Ariyaratne, D., Kalra, H., Boukouris, S., Mathew, N., Al Saffar, H., Gangoda,
L., Ang, C.S., Sieber, O., Mariadason, J., Dasgupta, R., Chilamkurti, N. and Mathivanan, S. (2016)
Colorectal Cancer Atlas: An integrative resource for genomic and proteomic annotations from colorectal cancer cell lines and tissue.
Nucleic Acids Research. 44(D1), D969-74.
52. Kalra, H., Drummen, G.P.C. and Mathivanan, S. (2016)
Focus on Extracellular Vesicles: Introducing the Next Small Big Thing.
International Journal of Molecular Sciences. 6;17(2).
51. Keerthikumar, S., Chisanga, D., Ariyaratne, D., Al Saffar, H., Anand, S., Zhao, K., Samuel, M., Pathan, M., Jois, M., Chilamkurti, N., Gangoda, L. and Mathivanan, S. (2016) ExoCarta: A web-based compendium of exosomal cargo.
Journal of Molecular Biology. 428, 688-692
50. Lowe, R., McCorkelle, O., Bleackley, M., Collins, C., Faou, P., Mathivanan, S. and Anderson, M. (2015)
Extracellular peptidases of the cereal pathogen Fusarium graminearum.
Frontiers in Plant Science. 6, 962.
49. Samuel, M., Bleackley, M., Anderson, M. and Mathivanan, S. (2015) Extracellular vesicles including exosomes in cross kingdom regulation:
a viewpoint from plant-fungal interactions. Frontiers in Plant Science. 6, 766.
48. Atkin-Smith, G.K., Tixeira, R., Paone, S., Mathivanan, S., Collins, C., Liem, M., Goodall, K.G., Ravichandran, K.S., Hulett, M.D. and Poon, I.V.H.
(2015)
A novel mechanism of generating extracellular vesicles during apoptosis via a beads-on-a-string membrane structure. Nature Communications. 6, 7439.
47. Pathan, M., Keerthikumar, S., Ang, C.S., Gangoda, L., Quek, C.M.J., Williamson, N.J., Mouradov, D., Sieber, O.M.,
Simpson, R.J., Salim, A., Bacic, A., Hill, A.F., Stroud, D.A., Ryan, M.T., Agbinya, J.A., Mariadasson, J.M., Burgess, A.W. and Mathivanan, S. (2015)
FunRich: a standalone tool for functional enrichment analysis. Proteomics. 15, 2597-2601.
46. Keerthikumar, S., Gangoda, L., Liem, M., Fonseka, P., Atukorala, I., Ozcitti, C., Mechler, A., Adda, C.G., Ang, C.S. and Mathivanan, S. (2015)
Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes.
Oncotarget. 17, 15375-15396.
45. Lydic, T.A., Townsend, S., Adda, C., Collins, C., Mathivanan, S. and Reid, G.E. (2015)
Rapid and comprehensive 'shotgun' lipidome profiling of colorectal cancer cell derived exosomes Methods. pii: S1046-2023.
44. Gangoda, L., Keerthikumar, S., Fonseka, P., Edgington, L.E., Ang, C.S., Ozcitti, C., Bogyo, M., Parker, B.S. and Mathivanan, S. (2015)
Inhibition of cathepsin proteases attenuates migration and sensitizes aggressive N-Myc amplified human neuroblastoma cells to doxorubicin.
Oncotarget. 6:13, 11175-11190.
43. Boukoris, S. and Mathivanan, S. (2015) Exosomes in bodily fluids are a highly stable resource of disease biomarkers. Proteomics clinical applications. 9, 358-67.
42. Kim DK, Lee J, Kim SR, Choi DS, Yoon YJ, Kim JH, Go G, Nhung D, Hong K, Jang SC, Kim SH, Park KS, Kim OY, Park HT,
Seo JH, Aikawa E, Baj-Krzyworzeka M, Van Balkom BW, Belting M, Blanc L, Bond V, Bongiovanni A, Borras FE, Buee L, Buzas EI, Cheng L,
Clayton A, Cocucci E, Dela Cruz CS, Desiderio DM, Di Vizio D, Ekstrom K, Falcon-Perez JM, Gardiner C, Giebel B, Greening DW, Gross JC, Gupta D, Hendrix A, Hill AF, Hill MM,
Hoen EN, Hwang DW, Inal J, Jagannadham MV, Jayachandran M, Jee YK, Jorgensen M, Kim KP, Kim YK, Kislinger T, Lasser C, Lee DS, Lee H, Van Leeuwen J, Lener T, Liu ML, Lotvall J, Marcilla A,
Mathivanan S, Moller A, Morhayim J, Mullier F, Nazarenko I, Nieuwland R, Nunes DN, Pang K, Park J, Patel T, Pocsfalvi G, Del Portillo H, Putz U, Ramirez MI,
Rodrigues ML, Roh TY, Royo F, Sahoo S, Schiffelers R, Sharma S, Siljander P, Simpson RJ, Soekmadji C, Stahl P, Stensballe A, Stepien E, Tahara H, Trummer A, Valadi H,
Vella LJ, Wai SN, Witwer K, Yanez-Mo M, Youn H, Zeidler R, Gho YS (2015) EVpedia: A Community Web Portal for Extracellular Vesicles Research. Bioinformatics. 31, 933-939.
41. Minciacchi, V.R., You, S., Spinelli, C., Morley, S., Zandian, M., Aspuria, P.J., Cavallini, L., Ciardiello, C., Sobreiro, M.R., Morello, M., Kharmate, G., Jang, S.C., Kim, D.K.,
Hosseini-Beheshti, E., Guns, E.T., Gleave, M., Gho, Y.S., Mathivanan, S., Yang, W., Freeman, M.R. and Di Vizio, D. (2015) Large oncosomes
contain distinct protein cargo and represent a separate functional class of tumor-derived extracellular vesicles. Oncotarget. 6:13, 11327-11341.
40. Gangoda, L., Boukouris, S., Liem, M., Kalra, H. and Mathivanan, S. (2015) Extracellular vesicles including exosomes
are mediators of signal transduction: Are they protective or pathogenic? Proteomics. 15:260-71.
39. Lotvall, J., Hill, A.F., Hochberg, F., Buzas, E.I., Di Vizio, D., Gardiner, C., Gho, Y.S., Kurochkin, I.V., Mathivanan, S., Quesenberry, P., Sahoo, S., Tahara, H., Wauben, M.H., Witwer, K.W. and Thery, C. (2014)
Minimal experimental requirements for definition of extracellular vesicles and their functions: a position statement from the International Society for Extracellular Vesicles.
Journal of Extracellular Vesicles. 3:26913.
38. Cossetti, C., Iraci, N., Mercer, T.N., Leonardi, T., Alpi, E., Drago, D., Alfaro-Cervello, C., Saini, H.K., Davis, M.P., Schaeffer, J., Vega, B.,
Stefanini, M., Zhao, C., Muller, W., Garcia-Verdugo, J.M., Mathivanan, S., Bachi, A., Enright, A.J., Mattick, J.S. and Pluchino, S. (2014)
Extracellular Vesicles from Neural Stem Cells Transfer IFN-γ via Ifngr1 to Activate Stat1 Signaling in Target Cells.
Molecular Cell. 56 (2), 193-204.
37. Cooke, I., Jones, D., Bowen, J., Denge, C., Faou, P., Hall, N., Jayachandran, V., Liem, M., Taranto, A., Plummer, K.M. and Mathivanan, S. (2014)
Proteogenomic analysis of the Venturia pirina (pear scab fungus) secretome reveals potential effectors. Journal of Proteome Research.
8, 3635-44
36. Mathivanan, S. (2014) Integrated bioinformatics analysis of the publicly available protein data shows evidence for 96% of the human proteome. Journal of Proteomics and Bioinformatics 7, 41-49.
35. Nanjappa, V., Thomas, J.K., Marimuthu, A., Muthusamy, B., Radhakrishnan, A., Sharma, R., Khan, A. A., Balakrishnan, L., Sahasrabuddhe, N., Kumar, S.,
Jhaveri, B.N., Sheth, K.V., Khatana, R.K., Shaw, P.G., Srikanth, S.M., Mathur, P.P., Shankar, S., Nagaraja, D., Christopher, R.,
Mathivanan, S., Raju, R., Sirdeshmukh, R., Chatterjee, A., Simpson, R., Harsha, H.C., Pandey, A. and Prasad, T.S.K. (2014)
Plasma Proteome Database as a resource for proteomics research: 2014 update. Nucleic Acids Research. 1, D959-65.
34. Kalra, H., Adda, C.G., Liem, M., Ang, C.S., Mechler, A., Simpson, R.J., Hulett, M.D. and Mathivanan, S. (2013) Comparative proteomics evaluation of plasma exosome isolation techniques and
assessment of the stability of exosomes in normal human blood plasma. Proteomics.
22, 3354-64.
31. Kalra, H., Simpson, R.J., Ji, H., Aikawa, E., Altevogt, P., Askenase, P., Bond, V.C., Borras, F.E., Breakefield, X., Budnik, V., Buzas, E.,
Camussi, G., Clayton, A., Cocucci, E., Falcon-Perez, J.M., Gabrielsson, S., Gho, Y.S., Gupta, D., Harsha, H.C., Hendrix, A., Hill, A.F., Inaal, J.M.,
Jenster, G., Kiang, L.S., Kramer-Albers, E-M., Llorente, A., Lotvall, J., Mincheva-Nilsson, L., Nazarenko, I., Nieuwland, R., Nolte-'t Hoen, E.N.M., Pandey, A.,
Patel, T., Piper, M.G., Pluchino, S., Prasad, T.S.K., Rajendran, L., Raposo, G., Record, M., Reid, G.E., Sanchez-Madrid, F., Schiffelers, R.M., Siljander, P.,
Stoorvogel, W., Taylor, D., Thery, C., Valadi, H., van Balkom, B.W.M., Vazquez, J., Vidal, M., Yanez-Mo, M., Zoeller, M. and
Mathivanan, S. (2012) Vesiclepedia: A compendium for extracellular vesicles with continuous community annotation. PLoS Biology. 12, e1001450.
23. Ji, H., Goode, R.J.A., Vaillant, F., Mathivanan, S., Kapp, E.A., Mathias, R.A., Linderman, G.J., Visvader, J.E., Simpson, R.J. (2011). Proteomic profiling of secretome and adherent plasma
membranes from distinct mammary epithelial cell subpopulations. Proteomics. 20, 4029-39.
18. Mathivanan, S., Hong, J. and Simpson, R.J. (2010). Exosomes: extracellular organelles important in intercellular communication. J Proteomics. 10, 1907-20.
15. Simpson, R. J., Lim, J. W. E., Moritz, R. L. and Mathivanan, S. (2009). Exosomes: proteomic insights and diagnostic potential. Expert reviews in proteomics. 6, 267-83.
10. Mathivanan, S. and Pandey, A. (2008). Human Proteinpedia as a resource for clinical proteomics. Mol Cell Proteomics. 10, 2038-47.
8. Molina, H., Horn, D. M., Tang, N., Mathivanan, S. and Pandey, A. (2007). Global Proteomic Profiling of Phosphopeptides using Electron Transfer Dissociation Tandem
Mass Spectrometry. Proceedings of the National Academy of Sciences, USA. 104, 2199-2204.
6. Mathivanan, S., Periaswamy, B., Gandhi, T. K. B., Kandasamy, K., Suresh, S., Mohmood, R., Ramachandra, Y. L. and Pandey, A. (2006). An Evaluation of Human Protein-Protein
Interaction Data in the Public Domain. BMC Bioinformatics. 7, S19.
3. Muthusamy, B., Hanumanthu, G., Reshmi, R., Sriranjini, S., Suresh, S., Rekha, B., Srinivas, D., Karthick, L., Vrushabendra, B. M., Sharma, S., Mishra, G.,
Rashmi, B. P., Kadekar, S., Chatterjee, P., Mangala, K. S., Shivashankar, H. N., Chandrika, K. N., Deshpande, N., Mathivanan, S., Kannabiran, N., et al. (2005). Plasma Proteome Database as a resource for
proteomics research. Proteomics. 5, 3531-3536. |